MSU School of Pharmacy

Welcome to the MSU School of Pharmacy's webpage.

Pharmacy Student's Orientation 2012

The First Pharmacy Student's Orientation in MSU by MPhC

Asian Federation for Pharmaceutical Science Conference 2011

Organizers and participants of Asian Federation for Pharmaceutical Science Conference 2011

Showing posts with label Pharmacy. Show all posts
Showing posts with label Pharmacy. Show all posts

Sunday, November 11, 2012

Beware Fake Drugs That Can Kill

PETALING JAYA: Some of the counterfeit drugs being sold in the country are dangerous and can kill, according to the Health Ministry.
The pharmacy enforcement division said a Bill was being drafted to increase the penalties for selling counterfeit drugs.
Division director Mohd Hatta Ahmad said that sex stimulants, painkillers and cough mixtures were among the drugs being counterfeited and sold cheaper than the genuine stuff.
Check the Meditag hologram label found on the product.
Check the Meditag hologram label found on the product.
The division had found that these fake products and others such as eye drops, cold preparations and ointments, were being sold in traditional medicine and sundry shops and roadside stalls, he told The Star.
The counterfeit products that it had seized were either manufactured locally or brought in from countries such as Indonesia, Thailand, the Philippines, India and China, he said.
Mohd Hatta Ahmad warned that consuming counterfeit sexual stimulants that contain sildenafil, tadalafil and verdanafil or slimming agents containing sibutramine without proper supervision from a medical doctor or pharmacist “can lead to serious consequences”.
“These counterfeit drugs can even cause death as they may destroy the body's vital organs and are also reported to cause mental disorders.”
Mohd Hatta stressed that all pharmaceutical products must be registered with the ministry before being marketed.
Fomca chief executive officer Datuk Paul Selvaraj advised the public to buy medication only from established premises and to obtain a doctor's prescription.
“If a medicine is cheaper, be suspicious. There must be a reason why it is cheaper,” he said.
Malaysian Medical Association president Dr S.R. Manalan said the onus was on the consumer to be wary.
“As long as you buy medicine bearing the Health Ministry's registration number, there is nothing to worry about,” he said.
On the new Bill, Mohd Hatta said that it would define clearly counterfeit medicinal products and provide for penalties of up to 10 times stiffer than the current punishment.
The division's statistics indicate that the sale of counterfeit drugs is not widespread, fortunately, and mostly involves popular over-the-counter and prescription medications of particular interest such as Viagra and Cialis.
“Recent studies have revealed the prevalence of counterfeit medicines to be between 3% and 6% in the market,” Mohd Hatta said.

Source: http://thestar.com.my/news/story.asp?file=/2012/9/9/nation/11996631&sec=nation

Thursday, September 13, 2012

An Aspirin a Day Lowers Cancer Mortality, New Data Confirm


August 10, 2012 — Results from a new study support the daily use aspirin to help prevent death from cancer.
However, questions remain about the size of the potential benefit, lead author Eric J. Jacobs, MD, from the American Cancer Society (ACS) in Atlanta, Georgia, told Medscape Medical News.
Dr. Eric Jacobs
"We were prompted to do the study because a recent analysis pooling results from existing randomized trials of daily aspirin for the prevention of vascular events found an estimated 37% reduction in cancer mortality among those using aspirin for 5 years or more [Lancet. 2012;379:1602–1612]," Dr. Jacobs said.
"But uncertainty remains about how much daily aspirin use may lower cancer mortality. The size of this pooled analysis was limited, and 2 very large randomized trials of aspirin taken every other day found no effect on overall cancer mortality," he explained.
To clarify how much daily aspirin use might lower the risk for fatal cancer, Dr. Jacobs and his colleagues analyzed information from 100,139 predominantly elderly participants in the Cancer Prevention Study II Nutrition Cohort who reported using aspirin on questionnaires.
The study was published online August 10 in the Journal of the National Cancer Institute.
The participants, who did not have cancer at the start of the study, were followed for up to 11 years.
The researchers found that daily aspirin use was associated with an estimated 16% lower overall risk for cancer mortality, both among people who reported taking aspirin daily for at least 5 years and among those who reported shorter-term daily use.
The reduction in overall cancer mortality was driven by a decrease of about 40% for cancers of the gastrointestinal tract (such as esophageal, stomach, and colorectal cancer) and a decrease of about 12% for cancers outside the gastrointestinal tract.
Too Soon to Recommend Aspirin to Prevent Cancer
"Although recent evidence about aspirin use and cancer is encouraging, it is still premature to recommend that people start taking aspirin specifically to prevent cancer," Dr. Jacobs said.
"Even low-dose aspirin can substantially increase the risk of serious gastrointestinal bleeding. Decisions about aspirin use should be made by balancing the risks against the benefits in the context of each individual's medical history, and any decision should be made only in consultation with a healthcare professional," he explained.
He added that expert committees developing clinical guidelines will consider the totality of the evidence on risks and benefits when guidelines for aspirin use are updated.
"I hope this study and other recent promising research about aspirin will lead to studies that look very carefully at daily aspirin use over long periods of time to more clearly understand aspirin's effects on specific cancers," Dr. Jacobs said.
Big Picture Is Positive
In an accompanying editorial, John A. Baron, MD, from the University of North Carolina School of Medicine in Chapel Hill, writes that "overall, the well-conducted ACS study is an echo of other data on aspirin and cancer mortality, not a resounding confirmation."
The "big picture" on aspirin use and cancer is "very positive," he noted. "The drug clearly reduces the incidence and mortality from luminal gastrointestinal cancers, and it may similarly affect other cancers. This is exciting: simply taking a pill can prevent cancer incidence and cancer death."
However, like Dr. Jacobs, Dr. Baron urges caution with regard to the widespread recommendation to use aspirin to prevent cancer.
Just because aspirin is effective "does not mean it necessarily should be used. Aspirin is a real drug, with definite toxicity. As for any preventive intervention, the benefits must be balanced against the risks, particularly when the benefits are delayed whereas the risks are not," he writes.
Dr. Jacobs has disclosed no relevant financial relationships. Dr. Baron reports being a consultant to Bayer, and holding a use patent for the chemopreventative use of aspirin, currently not licensed.
J Natl Cancer Inst. Published online August 10, 2012. Abstract, Editorial
Source: http://www.medscape.com/viewarticle/768917?src=mp

Tuesday, September 11, 2012

Pharmacist Seek RM5 Per Visit


With reference to the report entitled “Pharmacists seek RM5 per visit” (New Straits Times, 28 July 2012), the Ministry of Health is cognizant of the integral role played by pharmacists in the provision of healthcare in this country. Previously, pharmacists were mainly involved in the manufacturing, quality control and supply of medicines. Today, this has changed and pharmacists are actively involved in patient focused services and it is not uncommon for community pharmacists to provide services such as advice on the management of minor ailments, medication counselling, smoking cessation and weight management programs.

In most countries, pharmacists are paid a professional fee based on the services provided and the types of drugs dispensed. Currently, there is no standardised fee schedule in Malaysia for pharmacists unlike for doctors and dentists. For this to happen, there are several things which need to be put in place such as a fair drug pricing system, standardisation of service provision and a monitoring system by the government and the professional body itself.

Accreditation of community pharmacies against benchmarking standards has already been initiated through collaboration between the Ministry of Health, the Malaysian Pharmaceutical Society and the Malaysian Society for Quality in Health to ensure that they consistently deliver a high standard of care. The Ministry is also in the process of developing a medicines pricing system through which there will be uniformity in medicine charges. The introduction of mandatory continuing professional education will also help to ensure that practising pharmacists are equipped with up-to-date knowledge and that they provide the best standards of care to their clients.

The Ministry of Health will ensure that the public is not burdened when they seek professional help at the pharmacy and any form of remuneration is in line with fair medicines pricing and the provision of quality pharmaceutical services.


Dato’ Eisah Binti A. Rahman
Senior Director of Pharmaceutical Services
Ministry of Health Malaysia

Source: New Straits Times, 28 July 2012, Page 3 & MyPSA's Facebook Page

Tuesday, November 15, 2011

Home Medication Review (HMR)

HOME MEDICATION REVIEW
Duration; 14th November 2011

At 14th of November which is Monday, I followed the pharmacist in charge, Mr. Chan Chee Meng (U44) for the home medication review program. We went to the psychiatric ward located outside HTAR which is at Jalan Pegawai, Klang where the Klang Health Clinic and Klang Dental Clinic located about 10am. We were accompanied by a staff nurse Pn. Dermia, a medical assistant En. Amri, and a driver Mr. Kumar. In this program, we will go to the patient’s home to check for his/her compliance towards medicine and their progress. However, some patients went out when we did the visit. Mr. Chan said that they will contact the patients to notify them the next visit to their house. Some patients which are in critical condition will be given Clopixol Depot® 200mg/ml Inj. (Zuclopenthixol Decanoate) intramuscularly by the nurse or medical assistant. Among all the 12 patients visits, I found an interesting case of patient A which her mother complained the patient wake up very late in the morning because she sleep about 2am, and she would’t be able to move her body up after wake up from the sleep. After Mr. Chan checked the medicine dosage while the medical assistant checked the blood pressure and heart of the patient, they discussed with the doctor on phone to change the dosage of clozapine tablet 100mg OM and 500mg ON to 200mg OM and 400mg ON. Propanolol dosage reduced from 20mg BD to 20mg ON. The dosage of fluoxetine remains 60mg. Some patient’s family members really thanked us because patients developing positive progress on their mental health. We ended our visit about 2pm. Then, I followed Mr. Chan to his office and I started to ask him several questions. Next page is the explanation about Home Medication Review (HMR).
 
Introduction

Home Medication Review (HMR) is a patient-focused process which advocates the optimal and quality use of medication at the patient’s home. It involves systematic assessment of the patient’s medication in order to identify and meet the medication-related needs as well as to identify, resolve and prevent drug related problems.

This service is a continuation of patient’s care from health facilities to their home. It is a comprehensive activity which involves clarification of the indication for use and administration details of all prescription and non-prescription medicines (including nutritional supplements, vitamins, herbal/complementary medicine and other remedies) with access to medication storage.

Pharmacist as one of the important service providers in the health care system, are responsible for provision of information and advising patient or (care giver) regarding medications and therapeutic devices. They play a major role in monitoring and advocating patient’s awareness about safety, appropriate and quality use of medications and encourage compliance, in order to optimize therapeutic outcomes.
 
Objectives
Primary Objective
The objective of HMR is to improve health outcomes and quality of life of the patient by emphasizing the Quality Use of Medication, which is appropriate, safe, judicious and efficacious. The pharmacist works with the patient, doctors and other health care providers to evaluate medication related information as well as identifying, preventing and optimizing health outcomes. The best outcome of HMR is achieved by reconciling all medication related information including Prescription and Over the Counter (OTC) medicines, traditional medicines, health supplements as well as therapeutic devices and aids.

Secondary Objectives
• To monitor patients’ adherence towards medications especially patient suffering from chronic illness.
• To educate patients and their care givers pertaining to the importance of medication adherence and to address other medication related issues such as side effects and adverse drug reaction
• To ensure the right medication and the right amount are stored properly at patient’s home.
• To identify and resolve possible drug interaction involving all medicines involving all medicines including prescribed medicine, over the counter (OTC) medications, traditional as well as health supplements.
• To counsel patients and their care givers in order to improve their insight towards medication and overall well being.
• To facilitate a cooperative working relationship between the pharmacist and other members of the health care team in order to benefit the well being of the patient,
• To facilitate care givers involvement in the management of patient’s illness


Scope of Service
The HMR service is to be extended to patients who are currently seeking treatment in Ministry of Health Hospitals ans Community Health Clinics only.
Manpower Requirement
All appointments for HMR should be conducted by a qualified pharmacist. The HMR Pharmacist may accompany other health care team members if needed.
Appointment
Appointments or the number of visits for patients under the HMR program will be determined by the Pharmacist conducting the HMR.
Procedures
Patient Inclusion Citeria
The need of HMR lies on the treating doctor but any member of the health care team may trigger a potential need for HMR.
The citeria which may be used to determine the need of HMR are as follows:
• Patient suffering from chronic illness and taking five or more medications for long term therapy.
• Patients who are taking more than 12 doses of medications daily.
• Patients suspected of non-adherence or not managing well with medication-related therapeutic devices (such as inhalers or insulin pen).
• Patients who are managing their own medication but at risk due to language difficulties, impaired insight, confusion/dementia or any other cognitive difficulties such as psychiatric and geriatric patients.
• Patients who are taking medications with narrow therapeutic index or requiring therapeutic drug monitoring such as warfarin, phenytoin,digoxin etc.
• Patients who are recently discharged from hospital with significant change in medication regimen.
• Patients who have defaulted treatment or fail to refill their medication especially for chronic illness.
• Patients attending number of different doctors from the same health facility or receiving treatment from multiple health facilities.
• Symptoms requiring pharmaceutical intervention such as occurrence of adverse drug reaction or sub therapeutic response toward treatment.
Patient Exclusion Citeria
• Patients who are not Malaysian citizens.
• Patients who are homeless.
• Patients who are aggressive.
• Patient’s family who signed the consent form regarding unwillingness to join HMR.
Administrative Requirement
• HMR pharmacist need approval from Head of Department- official letter
• All HMR visits should be conducted after obtaining consent for visit from patient/care giver.
• Risk assessment should be done by the HMR pharmacist prior to visit, especially if the home visit is not to be conducted along with the community home care team.
Activities
ENROLLMENT OF PATIENTS FOR HMR
Pharmacist select HMR patients from the referral form from doctor. Then obtain consent from patient/caregiver to participate by filling up the consent form. Risk assessment applicable if HMR done by pharmacist alone.


PREPARATION BEFORE HOME VISIT
Make appointment with the patient/caregiver. Note down the appointment in HMR Appointment Record. Then prepare medication identification chart based on the patient case record. Then ensure all procedures in the checklist are adhered.
CONDUCTING HOME MEDICATION REVIEW
1. Introduce yourself and explain the purpose of the visit to the patient/care giver.
2. Initial assessment by HMR pharmacist.
3. Medication Adherence Evaluation using Modified Morisky Medication Adherence Scale.
4. Pharmacotherapy review
a) Identify pharmaceutical care issues
b) Plan interventions to address all the identified drug related problems
c) Discuss with the doctor pertaining to any change of regimen or other suggested intervention. To alert patient to come for follow up visit in clinic if needed.
5. Remind patient to attend the clinic on the appointment date with the doctor.
6. Distribute related pamphlets/leaflets to patient/care giver.
7. Remind patient/care giver to bring all the balance medication on next appointment with the doctor and return to pharmacy unit to get new supply based on new prescription.
8. Follow up visit will be held upon another referral from prescriber or when deemed appropriate by the HMR pharmacist.

Tuesday, February 22, 2011

Industrial Visit to CCM Duopharma Biotech Bhd



Hello readers,


School of Pharmacy had an industrial visit to CCM Duopharma Biotech Berhad which is the 1st pharmaceutical company producing generic drugs in Malaysia. The visit was held at 21st of February 2011 which falls on Monday scheduled at 2pm. The industrial visit idea was generated from the project manager, Chua Pei Yong.


Target student is 20 students accompanied by the Head of Department Mr. Mohd Fadli, lecturers Mr. Mohd Nizam and Dr. Jiyauddin Khan. The group was greeted warmly by the representative of CCM Duopharma, Puan Nurhariati and Mr Affandi. An interesting presentation basically on CCM Duopharma was given to the students about the generic products production at our country. They even launching for refilling human vaccines five years later and the first south east Asia who got this contract signed. Q and A session was interesting because the students were curious about the job opportunites in pharmaceutical industries.


They offered some refreshments and we had a rest before they bought us touring around the company. Firstly, we were bought to the water treatment system. According to Mr. Satish which was the person in-charge for water treatment system, the water plays vital roles for providing the desired quality of pharmaceutical products. The water treatment were using reverse osmosis (RO) system. After that, we are brought to the production department while can observed the making of pharmaceutical products such as tablets in a sterilized conditions with HEPA filters at box.


Then, we proceed to the warehouse department and we got to know how the pharmaceutical products being stored and its precautions. After that, we proceed to QC and QA department which was the last part of the trip. This is an open mind and informative industrial visit for the students. Hope the School of Pharmacy will organize this meaningful event again.

Monday, December 20, 2010

Nuclear pharmacy


Hello to all readers. How was your day?

Nuclear pharmacy, does that sound weird?

Nuclear pharmacy is a branch of pharmacy where dedicated to the compounding and dispensing of radioactive materials for use in nuclear medicine procedures.

The concept of nuclear pharmacy was first described in 1960 by Captain William H. Briner while at the National Institutes of Health (NIH) in Bethesda, Maryland. Along with Mr. Briner, John E. Christian, who was a professor in the School of Pharmacy at Purdue University, had written articles and contributed in other ways to set the stage of nuclear pharmacy


To be a nuclear pharmacist, he or she need to master physics and physical chemistry other than pharmacology and pharmaceutics subjects. This is because radioactive materials are involved in this work. Besides, they have to learn about radiography or imaging.

Required training

There are certain precautions that must be taken into account when handling radiopharmaceutical materials on a daily basis. Nuclear pharmacists receive extensive training on the various radiopharmaceuticals that they use. They are trained in radiation safety and other aspects specific to the compounding and preparation of radioactive materials. Many things are required to become pharmacists, but to become a nuclear pharmacist one must go through the following training:

1. 200 hours of classroom training in basic radioisotope handling techniques specifically applicable to the use of unsealed sources is required. The training should consist of lectures and laboratory sessions in the following areas:
Radiation physics and instrumentation
Radiation protection
Mathematics of radioactivity
Radiation biology
Radiopharmaceutical chemistry

2. 500 hours in handling unsealed radioactive material under a qualified instructor is also required. This experience should cover the type and quantities of by-product material requested in the application and includes the following:
Ordering, receiving, surveying, and unpackaging radioactive materials safely.
Calibration of dose calibrators, scintillation detectors, and survey meters
Calculation, preparation, and calibration of patient doses including the proper use of syringe shield.


Primary tasks of nuclear pharmacist include:
-Order, receipt, storage and inventory control of radioactive drugs (radiopharmaceuticals), other drugs used in nuclear medicine, and related supplies
-Preparation of radiopharmaceuticals by combining radioisotopes with reagent kits, and compounding radiopharmaceuticals that are not commercially available
-Functional checks of instruments, equipment and devices and determination of radiopharmaceutical quality and purity
-Filling of prescription orders
-Packaging, labeling and transport of radiopharmaceuticals
-Proper handling of hazardous chemicals and biological specimens
-Communicating radiopharmaceutical-related information to others
-Assuring that patients receive proper preparation before radiopharmaceutical administration and trouble-shooting unanticipated outcomes
-Laboratory testing of new radiopharmaceuticals, new compounding procedures, quality control methods and participation in clinical trials


Nuclear pharmacists work in a more relaxed environment compared to other areas of pharmacy, such as hospital pharmacy or retail pharmacy. There is usually no interaction with customers because many work in a highly regulated environment where consumers are not allowed.

Although the potential for radiation exposure exists in this field, it is kept to a minimum by the use of syringes, gloves, and other devices specifically designed for radioactive materials. A nuclear pharmacist would use leaded glass shielding, leaded glass syringe shields, and lead containers while working with radioactive material.

Hence, proper equipment and procedures reduce the risk of harm to personnel working in a nuclear pharmacy. Tungsten shielding is also used. While more expensive, it provides better shielding, does not break or deform like lead when dropped. It is also not toxic as lead is.


Muclear pharmacy do not develop rapidly compared to other branches of pharmacy such as pharmacognosy. It is new in Malaysia and only available at Hospital Universiti Sains malaysia at Kubang Kerian, Penang.

let's contribute to development of nuclear pharmacy in Malaysia through being a nuclear pharmacist. Happy reading! :D